Redetermination of 5α-androstane-3,17-dione
نویسندگان
چکیده
منابع مشابه
Redetermination of 5α-androstane-3,17-dione
The structure of the title compound, C(19)H(28)O(2), has been redermined at 295 (2) K, with much improved precision. The structure and mol-ecular packing of the title compound was first reported by Coiro et al. [Acta Cryst. (1973). B29, 1404-1409] by means of potential-energy calculations. The cell parameters in this study differ considerably in space group C2. It is a derivative of testosteron...
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The title compound, C(24)H(41)NO, is a new derivative of the anti-HIV steroid 17β-(N-tert-butyl-amino-carbon-yl)androst-4-en-3-one. There are four rings in the structure and these are trans-fused. The three six-membered rings exhibit chair conformations, while the five-membered ring adopts an envelope conformation.
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The title hydrated tetrol, C(19)H(32)O(4)·3H(2)O, was synthesized by stereoselective reduction of the compound 3β,5α,6β-trihy-droxy-androstan-17-one. All rings are fused trans. The organic mol-ecules are connected head-to-tail along the c axis via O-H⋯O hydrogen bonds. Layers of water mol-ecules in the ab plane inter-connect these chains. A quantum chemical ab initio Roothan Hartree-Fock calcul...
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The Rhodococcus erythropolis SQ1 kstD3 gene was cloned, heterologously expressed and biochemically characterized as a KSTD3 (3-keto-5α-steroid -dehydrogenase). Upstream of kstD3, an ORF (open reading frame) with similarity to 4 KSTD (3-keto-5α-steroid -dehydrogenase) was found, tentatively designated kst4D. Biochemical analysis revealed that the 1 KSTD3 has a clear preference for 3-ketosteroids...
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ژورنال
عنوان ژورنال: Acta Crystallographica Section E Structure Reports Online
سال: 2010
ISSN: 1600-5368
DOI: 10.1107/s1600536810019720